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Unnatural amino acid substitutions to improve in vivo stability and tumor uptake of 68 Ga-labeled GRPR-targeted TacBOMB2 derivatives for cancer imaging with positron emission tomography.

Lei WangHsiou-Ting KuoZhengxing ZhangChengcheng ZhangChao-Cheng ChenDevon ChappleRyan WilsonNadine Colponull François BénardKuo-Shyan Lin
Published in: EJNMMI radiopharmacy and chemistry (2024)
]Bombesin(7-14), is a promising template for use for the design of GRPR-targeted radiotherapeutic agents.
Keyphrases
  • positron emission tomography
  • pet ct
  • computed tomography
  • pet imaging
  • amino acid
  • cancer therapy
  • papillary thyroid
  • high resolution
  • squamous cell
  • lymph node metastasis
  • simultaneous determination