Tuberculosis and Coronavirus Disease 2019 (COVID-19) from A Clinical Perspective: A Systematic Review.
Tri Hari IrfaniPanoraia SiafakaRiska NabilaTungki Pratama UmarPublished in: Medeniyet medical journal (2020)
The aim of this review is to examine the effects of COVID-19 on Tuberculosis (TB) management and to highlight evidence of the extent of TB and COVID-19 co-infection. Current findings on TB and COVID-19 have been identified using six databases: Pubmed, Science Direct, Pubmed Central, MedXRiv, Wiley, and Google Scholar. This search in literature was conducted up to 8 May 2020. We included five studies that met the selection criteria. These selected studies have been performed in regions having various demographic characteristics including developed and developing countries, mainly China. The total number of participants in each study ranged from 24 to 203. The case fatality rate of patients with TB and COVID-19 co-infection was found to be high (6/49; 12.3 percent) while a combined diagnosis of TB and COVID-19 was found in 9/49 patients. This condition is linked to several complications, manifested as the need for ex novo oxygen supply, pneumothorax, and extreme hypoxia. Researches on BCG vaccination have shown that countries without vaccination policy are more likely to be seriously affected than those with BCG vaccination programs. COVID-19 infection in patients with TB or the lack of sufficient BCG vaccination may be associated with higher detrimental consequences, including mortality.
Keyphrases
- coronavirus disease
- mycobacterium tuberculosis
- sars cov
- respiratory syndrome coronavirus
- public health
- systematic review
- healthcare
- newly diagnosed
- ejection fraction
- cardiovascular events
- end stage renal disease
- hiv aids
- machine learning
- prognostic factors
- endothelial cells
- hiv infected
- hepatitis c virus
- tyrosine kinase
- human immunodeficiency virus
- artificial intelligence