Systematic characterization of a non-transgenic Aβ 1-42 amyloidosis model: synaptic plasticity and memory deficits in female and male mice.

injection, which underly cognitive deficits in the early stages of AD. These long-lasting cognitive and functional alterations in males and females validate this model for the study of early amyloidosis in both sexes, thus offering a solid alternative to the inconsistence of amyloidosis transgenic mice models.