Liver steatosis and metabolic dysfunction-associated fatty liver disease among HIV-positive and negative adults in urban Zambia.
Belinda Varaidzo ChihotaCarlotta RiebensahmGuy MuulaEdford SinkalaRoma ChilengiLloyd MulengaSamuel BosomprahMichael J VinikoorCarolyn Bolton-MooreMatthias EggerAndri RauchAnnalisa BerzigottiGilles Wandelernull nullPublished in: BMJ open gastroenterology (2022)
The prevalence of liver steatosis in this urban cohort of HIV-positive and negative adults in Zambia was low, despite a large proportion of patients with high BMI and central obesity. Our study is among the first to report data on MAFLD among adults in Africa, demonstrating that metabolic risk factors are key drivers of liver steatosis and supporting the adoption of the criteria for MAFLD in African populations.
Keyphrases
- hiv positive
- insulin resistance
- men who have sex with men
- risk factors
- high fat diet induced
- antiretroviral therapy
- south africa
- high fat diet
- human immunodeficiency virus
- metabolic syndrome
- electronic health record
- hiv infected
- weight gain
- adipose tissue
- body mass index
- type diabetes
- skeletal muscle
- big data
- physical activity
- deep learning