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[Investigation of the mutational status of the FGFR3 gene in urothelial bladder carcinoma].

E M OlyushinaL E ZavalishinaE Yu AlekseenokN A OskinaYulia Yu AndreevaO A KuznetsovaMaxim L FilipenkoG A Frank
Published in: Arkhiv patologii (2023)
gene was statistically significantly more common in the group of papillary low-grade non-muscle-invasive BC, demonstrating basal p16 IHC staining. In the study sample, there was no statistically significant relationship between the FGFR3 status of BC and gender and age differences, TILs, MMR status, PD-L1 status (SP142 and 22C3), and p16 status. The results of the study indicate the need to determine the FGFR3 status in patients with BC for further prescription of personalized therapy.
Keyphrases
  • low grade
  • high grade
  • genome wide
  • mental health
  • dna methylation
  • gene expression
  • copy number