BRAF V600 mutation profiling in primary skin nodular melanoma in Indonesia: an analysis using high resolution pyrosequencing.
Hanggoro Tri RinonceRovi Panji Mustiko AjiNi'mah HayatiMaria Fransiska PudjohartonoBidari KameswariSumadi Lukman Anwarnull IrianiwatiPublished in: BMC research notes (2020)
BRAF V600 mutations of the V600E type were found in 21 (53.85%) specimens. The variant allele frequencies (VAFs) ranged from 5.07 to 94.70%, averaging 29.05%. However, most cases had low VAFs, with 13 (61.9%) specimens below 20% and 4 (19.05%) below 10%.