Sex-specific declines in cholinergic-targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease.
Dana ShulmanSerafima DubnovTamara ZorbazNimrod MadrerIddo PaldorDavid A BennettSudha SeshadriElliott J MufsonDavid S GreenbergYonatan LoewensteinHermona SoreqPublished in: bioRxiv : the preprint server for biology (2023)
Our findings support CholinotRFs contributions to cholinergic regulation, predicting their involvement in AD sex-specific cholinergic loss and dementia.