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A near-infrared fluorescent nanoprobe for senescence-associated β-galactosidase sensing in living cells.

Ye ZhaoShan SunYan LyuMengyao GaoHengwei LinCheng Yang
Published in: Chemical communications (Cambridge, England) (2023)
A near-infrared fluorescent nanoprobe based on semiconducting polymer nanoparticles (SPNs) for the detection of senescence-associated β-gal (SA-β-gal) is developed. Benefiting from the intrinsic lysosome-locating feature, this probe can be successfully used for the visualization of SA-β-gal in living cells.
Keyphrases
  • living cells
  • fluorescent probe
  • single molecule
  • dna damage
  • endothelial cells
  • stress induced
  • machine learning
  • deep learning
  • oxidative stress
  • real time pcr
  • quantum dots