Epigenetic Silencing of SOX15 Is Controlled by miRNAs rather than Methylation in Papillary Thyroid Cancer.

Ahmet Özaydın Aysegul Soysal Betul Seyhan Soykan Arıkan Nejat Dalay Nur Buyru

Published in: Disease markers (2021)

Our results indicate that SOX15 gene expression is associated with the pathogenesis of papillary thyroid carcinoma (PTC), and the epigenetic control of the SOX15 gene is regulated by miRNAs rather than by promoter methylation.

Keyphrases

papillary thyroid
dna methylation
lymph node metastasis
gene expression
genome wide
transcription factor
stem cells
copy number
squamous cell carcinoma
genome wide identification