The role of the adipose tissue-derived mesenchymal stem cells enriched with melatonin on pancreatic cellular regeneration.

H El AasarL RashedAbir El SadikR AmerH Emam

Published in: Folia morphologica (2021)

The present study confirmed the potential therapeutic and protective role of MT pre-treated AD-MSCs against the STZ-induced pancreatic islet cells' damage. Further studies were recommended to investigate the efficacy of MT and AD-MSCs over longer experimental durations.

Keyphrases

adipose tissue
diabetic rats
mesenchymal stem cells
induced apoptosis
oxidative stress
stem cells
umbilical cord
high glucose
insulin resistance
high fat diet
type diabetes
skeletal muscle
endoplasmic reticulum stress
cell proliferation
newly diagnosed
bone marrow
cell death
stress induced