Identifying the Mechanisms and Molecular Targets of Yizhiqingxin Formula on Alzheimer's Disease: Coupling Network Pharmacology with GEO Database.
Tingting ZhangLinlin PanYu CaoNanyang LiuWei WeiHao LiPublished in: Pharmacogenomics and personalized medicine (2020)
YZQX against AD may exert its neuroprotective effect via the PI3K-Akt signaling pathway, MAPK signaling pathway, and ubiquitin-mediated proteolysis. YZQX may be a promising drug that can be used in the treatment of AD.
Keyphrases
- signaling pathway
- pi k akt
- epithelial mesenchymal transition
- induced apoptosis
- adverse drug
- small molecule
- oxidative stress
- emergency department
- cell proliferation
- room temperature
- human milk
- blood brain barrier
- combination therapy
- brain injury
- drug induced
- replacement therapy
- smoking cessation
- endoplasmic reticulum stress
- subarachnoid hemorrhage