Bone Remodeling Interaction with Magnesium Alloy Implants Studied by SEM and EDX.
Alexey DrobyshevAlexander KomissarovNicolai RedkoZaira GurganchovaEugene S StatnikViacheslav E BazhenovIuliia SadykovaAndrey MiterevIgor RomanenkoOleg YanushevichPublished in: Materials (Basel, Switzerland) (2022)
The development direction of bioresorbable fixing structures is currently very relevant because it corresponds to the priority areas in worldwide biotechnology development. Magnesium (Mg)-based alloys are gaining high levels of attention due to their promising potential use as the basis for fixating structures. These alloys can be an alternative to non-degradable metal implants in orthopedics, maxillofacial surgery, neurosurgery, and veterinary medicine. In our study, we formulated a Mg-2Zn-2Ga alloy, prepared pins, and analyzed their biodegradation level based on SEM (scanning electron microscopy) and EDX (energy-dispersive X-ray analysis) after carrying out an experimental study on rats. We assessed the resorption parameters 1, 3, and 6 months after surgery. In general, the biodegradation process was characterized by the systematic development of newly formed bone tissue. Our results showed that Mg-2Zn-2Ga magnesium alloys are suitable for clinical applications.
Keyphrases
- electron microscopy
- high resolution
- pet ct
- soft tissue
- minimally invasive
- heavy metals
- magnetic resonance
- computed tomography
- magnetic resonance imaging
- coronary artery disease
- risk assessment
- ionic liquid
- acute coronary syndrome
- mass spectrometry
- surgical site infection
- body composition
- atrial fibrillation
- bone regeneration
- contrast enhanced
- gas chromatography