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BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update.

Alena SavanevichOlgierd AshurykCezary CybulskiJan LubińskiJacek Gronwald
Published in: Hereditary cancer in clinical practice (2021)
The frequency of 13 causative BRCA1 and BRCA2 founder mutations in West Belarus was higher than in other Slavic countries. Testing of BRCA1 (c.5266dupC, c.4035delA, c.3756_3759delGTCT, c.68_69delAG, c.1687C > T as well as c.181 T > G) and BRCA2 (c.658_659delGT) mutations should be considered an inexpensive and sensitive test panel for this population.
Keyphrases
  • breast cancer risk
  • end stage renal disease
  • chronic kidney disease
  • ejection fraction
  • prognostic factors