BRCA1 and BRCA2 mutations in ovarian cancer patients from Belarus: update.
Alena SavanevichOlgierd AshurykCezary CybulskiJan LubińskiJacek GronwaldPublished in: Hereditary cancer in clinical practice (2021)
The frequency of 13 causative BRCA1 and BRCA2 founder mutations in West Belarus was higher than in other Slavic countries. Testing of BRCA1 (c.5266dupC, c.4035delA, c.3756_3759delGTCT, c.68_69delAG, c.1687C > T as well as c.181 T > G) and BRCA2 (c.658_659delGT) mutations should be considered an inexpensive and sensitive test panel for this population.