A genetic risk score and number of myopic parents independently predict myopia.

Neema Ghorbani-Mojarrad Cathy Williams Jeremy A Guggenheim

Published in: Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) (2018)

A GRS improved the ability to detect children at risk of myopia independently of knowing the NMP. We speculate this may be because NMP captures information concerning environmental risk factors for myopia. Nevertheless, further gains are required to make such predictive tests worthwhile in the clinical environment.

Keyphrases

optic nerve
young adults
copy number
gene expression
human health
dna methylation