Login / Signup

Threshold adjusted vagus nerve stimulation after asphyxial cardiac arrest results in neuroprotection and improved survival.

Rishabh C ChoudharyUmair AhmedMuhammad ShoaibEric AlperAbdul RehmanJunhwan KimKoichiro ShinozakiBruce T VolpeSangeeta ChavanStavros ZanosKevin J TraceyLance B Becker
Published in: Bioelectronic medicine (2022)
Our findings suggest that using tVNS for 2 h after 12 minutes of CA attenuates ischemia neuronal cell death, heart and kidney damage, and improves 72 h survival with improved neurological recovery.
Keyphrases
  • cardiac arrest
  • cell death
  • cerebral ischemia
  • cardiopulmonary resuscitation
  • free survival
  • heart failure
  • oxidative stress
  • brain injury
  • atrial fibrillation
  • blood brain barrier
  • cell cycle arrest
  • signaling pathway