Isocytosine deaminase Vcz as a novel tool for the prodrug cancer therapy.

Arūnas KazlauskasAdas DarinskasRolandas MeškysArimantas TamašauskasJaunius Urbonavičius

Published in: BMC cancer (2019)

We have confirmed that the novel ICD Vcz together with the non-toxic prodrug 5-FIC has a potential of being a new enzyme/prodrug system for suicide gene therapy.

Keyphrases

cancer therapy
gene therapy
drug delivery
drug release
climate change
human health