Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.

Rombout B E van AmstelJason N KennedyBrendon P SciclunaLieuwe D J BosHessel Peters-SengersJoe M ButlerEddie Cano-GamezJulian C KnightAlexander P J VlaarOlaf L CremerDerek C AngusTom van der PollChristopher W SeymourLonneke A van Vughtnull null

Published in: Intensive care medicine (2023)

Among critically ill patients with sepsis, subtype strategies using clinical, biomarker, and transcriptomic data do not identify comparable patient populations and are likely to reflect disparate clinical characteristics and underlying biology.

Keyphrases

septic shock
acute kidney injury
single cell
intensive care unit
case report
electronic health record
rna seq
big data
machine learning
artificial intelligence