Genetic diversity of Leishmania donovani that causes cutaneous leishmaniasis in Sri Lanka: a cross sectional study with regional comparisons.

Udeshika Lakmini KariyawasamAngamuthu SelvapandiyanKeshav RaiTasaduq Hussain WaniKavita AhujaMizra Adil BegHasitha Upendra PremathilakeNarayan Raj BhattaraiYamuna Deepani SiriwardenaDaibin ZhongGuofa ZhouSuman RijalHira NakhasiNadira Darshani Karunaweera

Published in: BMC infectious diseases (2017)

This study reveals high levels of haplotype diversity of L. donovani in Sri Lanka with a distinct genetic association with clinically relevant phenotypic characteristics. The use of genetic tools to identify clinically relevant features of Leishmania parasites has important therapeutic implications for leishmaniasis.

Keyphrases

genetic diversity
genome wide
copy number
physical activity
risk factors