Feasibility of 15O-water PET studies of auditory system activation during general anesthesia in children.

Martin MamachFlorian WilkeMartin DurisinFrank A BegerMareike FinkeAndreas BüchnerBarbara SchultzArthur SchultzLilli GeworskiFrank M BengelThomas LenarzAnke Lesinski-SchiedatGeorg Berding

Published in: EJNMMI research (2018)

Our data indicate that it is feasible to detect auditory cortex activations in 15O-water PET during general anesthesia. Combined with the improved signal to noise ratios of modern PET scanners, this suggests reasonable prospects for further evaluation of the method for clinical use in auditory implant users. Adapted parameters for data analysis seem to be helpful to improve the proportion of signals in AR versus eAR.

Keyphrases

data analysis
pet ct
positron emission tomography
working memory
computed tomography
hearing loss
pet imaging
air pollution
electronic health record
deep learning
case control