Outcome of Progressive Multifocal Leukoencephalopathy Treated by Interleukin-7.
Rebecca LajaunieIlaria MainardiJacques GasnaultVanessa RousseauAndrea G TarantinoAgnès SommetPaola CinqueGuillaume Martin-Blondelnull nullPublished in: Annals of neurology (2022)
In this non-controlled retrospective study, survival did not differ from that expected in HIV/AIDS patients, but might have been improved in those with hematological malignancies, primary immunodeficiencies and transplant recipients. RhIL-7 might have contributed to the increase in blood lymphocytes and decrease in CSF JCV replication that were associated with better survival. ANN NEUROL 2022;91:496-505.