Ammonium tetrathiomolybdate following ischemia/reperfusion injury: Chemistry, pharmacology, and impact of a new class of sulfide donor in preclinical injury models.
Alex DysonFelipe Dal-PizzolGiovanni SabbatiniAnna B LachFederica GalfoJuliano Dos Santos CardosoBruna Pescador MendonçaIain HargreavesBernardo Bollen PintoDaniel I BromageJohn F MartinKevin P MooreMartin FeelischMervyn SingerPublished in: PLoS medicine (2017)
The inorganic thiometallate ATTM represents a new class of sulfide-releasing drugs. Our findings provide impetus for further investigation of this compound as a novel adjunct therapy for reperfusion injury.