Maternal and Fetal Outcomes among Pregnant Women with Diabetes.
Miroslava GojnicJovana TodorovicDejana StanisavljevicAleksandra JoticLjiljana LukicTanja MilicicNebojsa LalicKatarina LalicMilica StoiljkovicTamara StanisavljevicAleksandar StefanovicKatarina StefanovicSvetlana Vrzic-PetronijevicMilos PetronijevicZorica Terzic-SupicMaja MacuraMilan PerovicSandra BabićPavle PiperacMarija JovanovicBijana ParapidKrisitna DoklesticRadmila CerovicSinisa DjurasevicStefan DugalicPublished in: International journal of environmental research and public health (2022)
The aim of this study was to examine the differences in pregnancy complications, delivery characteristics, and neonatal outcomes between women with type 1 diabetes mellitus (T1DM), type 2 diabetes mellitus (T2DM), and gestational diabetes mellitus (GDM). This study included all pregnant women with diabetes in pregnancy in Belgrade, Serbia, between 2010 and 2020. The total sample consisted of 6737 patients. In total, 1318 (19.6%) patients had T1DM, 138 (2.0%) had T2DM, and 5281 patients (78.4%) had GDM. Multivariate logistic regression with the type of diabetes as an outcome variable showed that patients with T1DM had a lower likelihood of vaginal delivery (OR: 0.73, 95% CI: 0.64-0.83), gestational hypertension (OR: 0.47, 95% CI: 0.36-0.62), higher likelihood of chronic hypertension (OR: 1.88, 95% CI: 1.55-2.29),and a higher likelihood ofgestational age at delivery before 37 weeks (OR: 1.38, 95% CI: 1.18-1.63) compared to women with GDM. Multivariate logistic regression showed that patients with T2DM had a lower likelihood ofgestational hypertension compared to women with GDM (OR: 0.37, 95% CI: 0.15-0.92).Our results indicate that the highest percentage of diabetes in pregnancy is GDM, and the existence of differences in pregnancy complications, childbirth characteristics, and neonatal outcomes are predominantly between women with GDM and women with T1DM.
Keyphrases
- glycemic control
- type diabetes
- pregnancy outcomes
- end stage renal disease
- cardiovascular disease
- blood pressure
- newly diagnosed
- ejection fraction
- chronic kidney disease
- pregnant women
- preterm birth
- prognostic factors
- physical activity
- body mass index
- insulin resistance
- patient reported outcomes
- patient reported
- drug induced