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Anti-growth Effects of Imatinib and GNF5 via Regulation of Skp2 in Human Hepatocellular Carcinoma Cells.

Sung Hyun KimMyoung-Ok KimKi-Rim Kim
Published in: Journal of cancer prevention (2018)
These results suggest that the anti-growth activity of tyrosine kinase inhibitors may be associated with the regulation of p27/p21 and caspases through Skp2 blockage in HCC cells.
Keyphrases
  • induced apoptosis
  • endothelial cells
  • chronic myeloid leukemia
  • cell cycle arrest
  • signaling pathway
  • endoplasmic reticulum stress
  • cell proliferation
  • pi k akt