The association between inflammatory markers in blood and cerebrospinal fluid: a systematic review and meta-analysis.
Frederieke A J GigaseEmma SmithBrett CollinsKendall MooreGijsje J L J SnijdersDaniel KatzVeerle BerginkM Mercedes Perez-RodriquezLotje D de WittePublished in: Molecular psychiatry (2023)
This systematic review and meta-analysis revealed poor correlation between peripheral and central inflammatory markers in paired blood-CSF samples, with increased correlations in certain study populations. Based on the current findings, peripheral inflammatory markers are a poor reflection of the neuroinflammatory profile.