Tracking the Temporal Footprint Effect of Thermonociception and Denervation on the Brain's Pain Matrix: fMRI and BOLD Study in Rats.
Francisco PellicerJuan M Ortega-LegaspiRodrigo MartínSergio Solís-NájeraLucía Magis-WeinbergMartha León-OleaAriel Graff-GuerreroCamilo de la Fuente-SandovalAlfredo Odon RodriguezPublished in: Journal of pain research (2022)
The study shows for the first time continuous activation of the pain matrix following an acute thermal nociceptive stimulus followed by neuropathic damage. These results have given insight into the early stages of the development of neuropathic pain in vivo.