Detection of pathological contrast enhancement with synthetic brain imaging from quantitative multiparametric MRI.

Graziella Donatelli Gianmichele Migaleddu Matteo Cencini Paolo CecchiClaudio D'AmelioLuca Peretti Guido Buonincontri Michela Tosetti Mauro Costagli Mirco Cosottini

Published in: Journal of neuroimaging : official journal of the American Society of Neuroimaging (2024)

QTI-derived post-contrast synthetic T1-weighted imaging captures pathological contrast enhancement in most intracranial enhancing lesions. Further comparative studies employing quantitative imaging with higher spatial resolution is needed to support our data and explore possible future applications in clinical trials.

Keyphrases

high resolution
contrast enhanced
magnetic resonance
clinical trial
magnetic resonance imaging
computed tomography
multiple sclerosis
big data
white matter
single molecule
cerebral ischemia
functional connectivity
case control