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Regeneration and development. An amphibian call to arms.

Paul A KhanMichael J Crawford
Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2020)
Based upon these morphological clues, we conclude that larval regenerates are unlikely to exhibit features of epimorphic regeneration seen in adults, but are more likely to represent a form of developmental regulation. Furthermore, we confirm that post-metamorphic limb regeneration is not a simple recapitulation of ontology at the morphological level. These distinctions may help to explain and interpret some experiments and observations of regeneration in neotenic or paedomorphic urodeles.
Keyphrases
  • stem cells
  • wound healing
  • drosophila melanogaster