Risk factors of secondary cancer in laryngeal, oropharyngeal, or hypopharyngeal cancer after definitive therapy.
Goshi NishimuraHideaki TakahashiDaisuke SanoYasuhiro AraiTakashi HatanoYosuke KitaniNobuhiko OridatePublished in: International journal of clinical oncology (2023)
Patients with hypopharyngeal cancer require close follow-up as they are at high risk of developing secondary cancer, possibly because out-of-field radiation exposure may induce systemic secondary carcinogenesis in hypopharyngeal cancer patients with genetic abnormality induced by alcohol consumption.