Direct C-H alkylation of 3,4-dihydroquinoxaline-2-ones with N -(acyloxy)phthalimides via radical-radical cross coupling.

We present an organophotoredox-catalyzed direct Csp 3 -H alkylation of 3,4-dihydroquinoxalin-2-ones employing N -(acyloxy)pthalimides to provide corresponding products in good yields. A broad spectrum of NHPI esters (1°, 2°, 3°, and sterically encumbered) participates in the photoinduced alkylation of a variety of 3,4-dihydroquinoxalin-2-ones. In general, mild conditions, broad scope with good functional group tolerance, and scalability are the salient features of this direct alkylation process.