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Novel variants in POLH and TREM2 genes associated with a complex phenotype of xeroderma pigmentosum variant type and early-onset dementia.

Izadora Fonseca Zaiden SoaresDenise Maria ChristofoliniLis Gomes SilvaDavid FederAlzira Alves de Siqueira Carvalho
Published in: Molecular genetics & genomic medicine (2020)
This paper describes a rare case of a patient with two novel variants in the same chromosome associated with XPV and early-onset dementia.
Keyphrases
  • early onset
  • rare case
  • copy number
  • mild cognitive impairment
  • late onset
  • cognitive impairment
  • case report
  • genome wide