Magnetic hydrophobic-charge induction adsorbents for the recovery of immunoglobulins from antiserum feedstocks by high-gradient magnetic fishing.
Cláudia Sg GomesAdedayo FashinaAlfred Fernández-CastanéTimothy W OvertonTimothy J HobleyEirini TheodosiouOwen R T ThomasPublished in: Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) (2018)
Fast magnetic particle based capture of antibodies from an unclarified high-titre feed has been demonstrated. Efficient product recovery from ultra-high titre bioprocess liquors by high-gradient magnetic fishing requires that improved magnetic adsorbents displaying high selectivity, ultra-high capacity and operational robustness are used with 'state-of-the-art' rotor-stator magnetic separators. © 2018 The Authors. Journal of Chemical Technology & Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.