A microRNA binding site polymorphism in the 3' UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis.

Sai Sushmitha KonthamCharles Emmanuel Jebaraj WalterZioni Sangeetha ShankaranArvind RamanathanNirmala KaruppasamyThanka Johnson

Published in: Journal of the Egyptian National Cancer Institute (2022)

Our results indicate that VEGF-A +936C/T polymorphism is not a risk factor for developing CRC in Caucasian and South Asian population. However, the East Asian population was related to an increased risk of developing colorectal cancer due to the presence of the minor allele.

Keyphrases

vascular endothelial growth factor
endothelial cells
gene expression
african american