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Position statement from the Brazilian Society of Nephrology regarding chloroquine and hydroxychloroquine drug dose adjustment according to renal function.

Vinicius Daher Alvares DelfinoAna Maria Misael da SilvaDirceu Reis da SilvaRonaldo D'AvilaMaria Claudia Cruz AndreoliAngiolina KraycheteKleyton BastosMarcelo Mazza do Nascimento
Published in: Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia (2020)
Chloroquine and hydroxychloroquine have shown promising preliminary results and have been discussed as therapeutic options for patients with Covid-19. Despite the lack of robust evidence demonstrating the benefits and justifying the use of one of these drugs, the final decision is the responsibility of the attending physician and should be individualized and shared, whenever possible. This position statement recommends dosage adjustment for these drugs in the context of renal impairment.
Keyphrases
  • primary care
  • plasmodium falciparum
  • drug induced
  • decision making
  • adverse drug