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Alginate-Encapsulated Mesenchymal Stromal Cells Improve Hind Limb Ischemia in a Translational Swine Model.

Juline N DeppenSydney C GinnErica O TangLanfang WangMaegan L BrockmanRebecca D Levit
Published in: Journal of the American Heart Association (2024)
This study demonstrates the promise of the mesenchymal stromal cell secretome at improving peripheral artery disease outcomes and the potential for this novel swine model to serve as a component of the preclinical pipeline for advanced therapies.
Keyphrases
  • bone marrow
  • peripheral artery disease
  • cell therapy
  • stem cells
  • single cell
  • mesenchymal stem cells
  • big data
  • metabolic syndrome
  • adipose tissue
  • risk assessment
  • glycemic control
  • wound healing