Alginate-Encapsulated Mesenchymal Stromal Cells Improve Hind Limb Ischemia in a Translational Swine Model.

Juline N DeppenSydney C GinnErica O TangLanfang WangMaegan L Brockman Rebecca D Levit

Published in: Journal of the American Heart Association (2024)

This study demonstrates the promise of the mesenchymal stromal cell secretome at improving peripheral artery disease outcomes and the potential for this novel swine model to serve as a component of the preclinical pipeline for advanced therapies.

Keyphrases

bone marrow
peripheral artery disease
cell therapy
stem cells
single cell
mesenchymal stem cells
big data
metabolic syndrome
adipose tissue
risk assessment
glycemic control
wound healing