Sex differences in clinical and angiographic characteristics in spontaneous coronary artery dissection.
Filippo ZilioSimone MuragliaFabiola MoratMarco BorghesiDaniel TodaroAlberto MenottiMichele DallagoGiuseppe BraitoRoberto BonmassariPublished in: Future cardiology (2020)
Background: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome, mostly in women; however, differences between the sexes should be investigated. Materials & methods: Hundred consecutive patients affected by SCAD were identified; coronary lesions were classified according to the most recent classification and clinical and angiographic data of men and women were compared. Results: Men were significantly younger than women, with more cardiovascular risk factors. Lesions were prevalently classified as type 2A, type 2B or type 1; an angiographic pattern compatible with the presence of an intimal tear (types 1 and 1/2) was more represented in males. Conclusion: Sex-related differences in clinical and angiographic characteristics could help in shedding light on mechanisms that contribute to SCAD.
Keyphrases
- coronary artery
- cardiovascular risk factors
- acute coronary syndrome
- pulmonary artery
- end stage renal disease
- chronic kidney disease
- coronary artery disease
- machine learning
- cardiovascular disease
- ejection fraction
- newly diagnosed
- heart failure
- polycystic ovary syndrome
- type diabetes
- prognostic factors
- atrial fibrillation
- skeletal muscle
- antiplatelet therapy
- pulmonary arterial hypertension
- left ventricular
- transcatheter aortic valve replacement
- mass spectrometry
- aortic stenosis
- atomic force microscopy
- patient reported outcomes
- cervical cancer screening
- high speed