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Does Intensive Treatment Select for Praziquantel Resistance in High-Transmission Settings? Parasitological Trends and Treatment Efficacy Within a Cluster-Randomized Trial.

John Vianney TushabeLawrence LubyayiJoel SserubanjaProssy KabuubiElson AbayoSamuel KiwanukaJacent NassuunaJames KaweesaPaul CorstjensGovert van DamRichard E SanyaWilliam SsenyongaEdridah Muheki TukahebwaNarcis B KabatereineAlison M ElliottEmily L Webbnull null
Published in: Open forum infectious diseases (2020)
In this schistosomiasis hot spot, there was little evidence of decreased praziquantel efficacy. However, in the absence of alternative therapies, there remains a need for continued vigilance of praziquantel efficacy in the MDA era.
Keyphrases
  • cell death
  • combination therapy