Antiulcerogenic Activity of Li-Zhong Decoction on Duodenal Ulcers Induced by Indomethacin in Rats: Involvement of TLR-2/MyD88 Signaling Pathway.

Houpan Song Meiyan Zeng Xiaojuan Chen Xinyi Chen Jun Peng Ye Lin Rong Yu Xiong Cai Qing-Hua Peng

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

Our data demonstrate that LZD protects the duodenal mucosa from IND-caused lesions, which is at least partially attributable to the interaction of its potential cytoprotective and anti-inflammatory mechanisms together with enhancement of the mucosal immunity through TLR-2/MyD88 signaling pathway.

Keyphrases

toll like receptor
signaling pathway
inflammatory response
pi k akt
anti inflammatory
nuclear factor
immune response
epithelial mesenchymal transition
induced apoptosis
electronic health record
cell proliferation
big data
ulcerative colitis
oxidative stress
data analysis