M2 macrophage is the predominant phenotype in airways inflammatory lesions in patients with granulomatosis with polyangiitis.
Alexandre Wagner Silva de SouzaMirjan van TimmerenJan-Stephan SandersCoen StegemanPeter HeeringaCees G M KallenbergJohanna WestraPublished in: Arthritis research & therapy (2017)
In GPA, M2 is the predominant macrophage phenotype in the respiratory tract. Although some associations were observed between macrophages and T cells with therapy and nasal carriage of Staphylococcus aureus, they were not independently significant in multivariate analysis.