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M2 macrophage is the predominant phenotype in airways inflammatory lesions in patients with granulomatosis with polyangiitis.

Alexandre Wagner Silva de SouzaMirjan van TimmerenJan-Stephan SandersCoen StegemanPeter HeeringaCees G M KallenbergJohanna Westra
Published in: Arthritis research & therapy (2017)
In GPA, M2 is the predominant macrophage phenotype in the respiratory tract. Although some associations were observed between macrophages and T cells with therapy and nasal carriage of Staphylococcus aureus, they were not independently significant in multivariate analysis.
Keyphrases
  • respiratory tract
  • staphylococcus aureus
  • adipose tissue
  • cystic fibrosis
  • oxidative stress
  • data analysis
  • stem cells
  • escherichia coli
  • smoking cessation