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Two placebo-controlled crossover studies in healthy subjects to evaluate gastric acid neutralization by an alginate-antacid formulation (Gaviscon Double Action).

Joanne WilkinsonKhalid Abd-ElazizIzaak den DaasJohan WemerMichiel van HaastertVictoria HodgkinsonMichelle FosterCathal Coyle
Published in: Drug development and industrial pharmacy (2018)
These studies demonstrate the effective acid neutralizing capacity of Gaviscon DA versus placebo in healthy, fasted subjects. This adds to the evidence base for the combination of alginates and antacids.
Keyphrases
  • placebo controlled
  • double blind
  • case control
  • phase iii
  • clinical trial
  • study protocol
  • drug delivery
  • phase ii
  • open label
  • phase ii study