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Anti-inflammatory cerium-containing nano-scaled mesoporous bioactive glass for promoting regenerative capability of dental pulp cells.

Yiyuan DuanKai ZhengWenzhu HuJake Jinkun ChenXiaolin LuMingxin WangYuxin YangJingyao GuoYanlai LuQian Ma
Published in: International endodontic journal (2024)
Ce-MBGNs protected cells from self-produced oxidative damage and exhibited excellent immunomodulatory and odontoblastic differentiation effects on DPCs. As a pulp-capping agent, this novel biomaterial can exert anti-inflammatory effects and promote restorative dentine regeneration in clinical treatment. We believe that this study will stimulate further correlative research on the development of advanced pulp-capping agents.
Keyphrases
  • stem cells
  • anti inflammatory
  • induced apoptosis
  • tissue engineering
  • mesenchymal stem cells
  • cell cycle arrest
  • cell therapy
  • signaling pathway
  • combination therapy
  • highly efficient