Transpulmonary pressures in obese and non-obese COVID-19 ARDS.
Mehdi MezidiFlorence DavietPaul ChabertSami HraiechLaurent BitkerJean-Marie ForelHodane YonisInes GraguebFrancois DhelftLaurent PapazianJean-Christophe RichardChristophe GuervillyPublished in: Annals of intensive care (2020)
Fifteen patients were investigated, 8 obese and 7 non-obese patients. PEEP ≥ 16 cm H2O for obese patients and PEEP ≥10 cm H2O for non-obese patients were necessary to obtain positive expiratory PL. Change of PEEP did not alter significantly ΔPL or elastances in obese patients. However, in non-obese patients lung EL and ΔPL increased significantly with PEEP increase. Chest wall EL was not affected by PEEP variations in both groups.
Keyphrases
- obese patients
- bariatric surgery
- gastric bypass
- roux en y gastric bypass
- weight loss
- end stage renal disease
- coronavirus disease
- sars cov
- acute respiratory distress syndrome
- mechanical ventilation
- adipose tissue
- prognostic factors
- metabolic syndrome
- peritoneal dialysis
- type diabetes
- intensive care unit
- extracorporeal membrane oxygenation
- mass spectrometry
- high resolution