Risk Factors for Amputation in the Surgical Treatment of Hemophilic Osteoarthropathy: A 20-Year Single-Center Report.

Yiming Xu Xisheng Weng Wei Zhu Yingjie Wang Xisheng Weng

Published in: Pain research & management (2022)

. As the first study on amputations in HO patients, we found that severe hemophilic pseudotumor, chronic bacterial infection, and coagulation factor inhibitor was potential risk factors for amputation. Sufficient factor replacement therapy is fundamental in the prevention of amputation. The early diagnosis and specially designed surgical techniques could improve the rate of limb salvage.

Keyphrases

replacement therapy
lower limb
end stage renal disease
peripheral artery disease
ejection fraction
chronic kidney disease
newly diagnosed
smoking cessation
early onset
prognostic factors
patient reported outcomes
cell proliferation
pi k akt
patient reported