Which Patients With Rhabdomyosarcoma Need Radiotherapy? Analysis of the Radiotherapy Strategies of the CWS-96 and CWS-2002P Studies and SoTiSaR Registry.
Bernarda KazanowskaBeate TimmermannMarc MünterJadwiga Weclawek-TompolRuth Lydia LadensteinFelix K NiggliGustaf LjungmanInes B BrechtBernd BlankErika HallmenMonika ScheerJoerg FuchsGuido SeitzClaudia BlattmannMonika Sparber-SauerThomas KlingebielPublished in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
RT can be omitted in patients with IRS I eRMS. RT improves LCS and EFS in IRS II and III. RT improves OS in patients with HN-PM, with proton RT comparable with photon RT. Doses of 32 Gy (HART) or 36 and 41.4 Gy (CFRT) had comparable efficacy in patients with favorable risk profiles and 44.8 Gy (HART) or 50.4 and 55.8 Gy (CFRT) in the unfavorable groups.