Bone marrow mesenchymal stem cells derived miRNA-130b enhances epithelial sodium channel by targeting PTEN.

Honglei ZhangYan DingYapeng HouYanhong LiuZhiyu ZhouHong-Guang Nie

Published in: Respiratory research (2020)

In summary, miRNA-130b in BMSCs can enhance ENaC at least partially by targeting PTEN and activating PI3K/AKT pathway, which may provide a promising new direction for therapeutic strategy in ALI.

Keyphrases

pi k akt
cell proliferation
signaling pathway