Bendamustine is a safe and effective lymphodepletion agent for axicabtagene ciloleucel in patients with refractory or relapsed large B-cell lymphoma.
Sushma BharadwajEric LauMark P HamiltonAnmol GoyalHrishi SrinageshAlexandria JensenDasom LeeJayasindhu MallampetSarah ElkordyShriya SyalSunita PatilTheresa LatchfordBita SahafSally AraiLaura J JohnstonRobert LowskyRobert NegrinAndrew R RezvaniJudith ShizuruEverett H MeyerParveen ShirazLekha MikkilineniWen-Kai WengMelody SmithSurbhi SidanaLori MufflyHolden T MaeckerMatthew J FrankCrystal MackallDavid MiklosSaurabh DahiyaPublished in: Journal for immunotherapy of cancer (2024)
Bendamustine is a safe and effective alternative lymphodepletion conditioning for axi-cel with lower early hematological toxicity and favorable immune reconstitution.