High sensitivity of domestic pigs to intravenous infection with HEV.

Lisa DähnertMartin EidenJosephine SchlosserChristine FastCharlotte SchröderElke LangeAlbrecht GrönerWolfram SchäferMartin Hermann Groschup

Published in: BMC veterinary research (2018)

The results indicate that pigs are highly susceptible to i.v. infection with HEV and that the swine model represents the most sensitive infectivity assay for HEV so far. Considering a minimum infectious dose of 24 IU RNA/ml our findings highlights the potential risk of HEV transmission via blood and blood products.

Keyphrases

high throughput
high dose
low dose
risk assessment
human health
nucleic acid
climate change