Optimization of human umbilical cord blood-derived mesenchymal stem cell isolation and culture methods in serum- and xeno-free conditions.

Liem Thanh NguyenNghia Trung TranUyen Thi Trang ThanMinh Quang NguyenAnh Minh TranPhuong Thi Xuan DoThao Thi ChuTu Dac NguyenAnh Viet BuiTien Anh NgoVan Thanh HoangHoang Thi My Nhung

Published in: Stem cell research & therapy (2022)

UCB-MSCs could be high-yield isolated and expanded under serum- and xeno-free conditions by using the StemMACS™ MSC Expansion Media kit. Autologous serum coating and plasma supplement enhanced cell proliferation. These UCB-MSCs had effected the tube formation process and an anti-cancer impact.

Keyphrases

mesenchymal stem cells
cord blood
cell proliferation
umbilical cord
bone marrow
cell therapy
stem cells
cell cycle
pi k akt