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Assessment of Neurovascular Uncoupling: APOE Status is a Key Driver of Early Metabolic and Vascular Dysfunction.

Kristen OnosPeter B LinRavi S PandeyScott A PersohnCharles P BurtonEthan W MinerKierra EldridgeJonathan Nyandu KanyindaKate E FoleyGregory W CarterGareth R HowellPaul R Territo
Published in: bioRxiv : the preprint server for biology (2024)
status in AD progression manifest as neurovascular uncoupling driven by immunological activation, and may serve as an early diagnostic biomarker.
Keyphrases
  • nitric oxide synthase
  • cognitive decline
  • oxidative stress
  • high fat diet
  • adipose tissue
  • mild cognitive impairment
  • skeletal muscle