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Folic acid ameliorates palmitate-induced inflammation through decreasing homocysteine and inhibiting NF-κB pathway in HepG2 cells.

Molood BagheriehAsma KheirollahiFahimeh Zamani-GarmsiriSolaleh EmamgholipourReza Meshkani
Published in: Archives of physiology and biochemistry (2021)
Overall, these results suggest that FA reduces inflammation in HepG2 cells through decreasing ROS and Hcy concentration level resulting in inhibiting the NF-κB pathway.
Keyphrases
  • signaling pathway
  • oxidative stress
  • diabetic rats
  • pi k akt
  • lps induced
  • dna damage
  • high glucose
  • cell death
  • reactive oxygen species
  • inflammatory response
  • cell proliferation
  • immune response