Benefits and harms of pregabalin in the management of neuropathic pain: a rapid review and meta-analysis of randomised clinical trials.

Igho J Onakpoya Elizabeth T ThomasJoseph J LeeBen GoldacreCarl J Heneghan

Published in: BMJ open (2019)

Pregabalin has beneficial effects on some symptoms of neuropathic pain. However, its use significantly increases the risk of a number of adverse events and discontinuation due to adverse events. The quality of the evidence from journal publications is low.

Keyphrases

neuropathic pain
clinical trial
spinal cord
spinal cord injury
open label
double blind
phase ii
study protocol
quality improvement
sleep quality
placebo controlled
loop mediated isothermal amplification
depressive symptoms